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Mode of onset, distribution of symptoms, and electrophysiological characteristics may be prognostic factors for predicting a favourable outcome.
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Although the tau negative and positive histologies are predicted to some extent by the clinical onset, the extent of the overlap and the convergence of the syndromes in the course of the disease argue in favor of maintaining the clinical and pathological varieties under a single umbrella.
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In a consecutive case series of 18 patients with severe essential tremor who underwent implantation of bilateral thalamic DBS electrodes, high-frequency stimulation resulted in significant, long-term improvement in their quality of life.
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Whole body fluorodeoxyglucose positron emission tomography scanning helps uncover the associated tumor, and recently proposed criteria may assist in the diagnosis. In many instances, prompt treatment of the tumor and immunotherapy result in symptom stabilization or neurologic improvement.
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In a randomized trial comparing immediate radiation therapy to delayed treatment in patients who underwent primary surgical resection of low-grade gliomas, overall survival was not significantly different between the 2 groups.
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The probability of in-hospital death was higher for patients with the lowest total FOUR score than for those with the lowest total GCS score.
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There is a role for endovascular therapy, such as stenting, as reported in Stroke, in the setting of failed medical management with anticoagulants.
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The results of this study underline the uncertainty regarding the risk/benefit ratio of rtPA treatment in acute stroke in patients older than 80 years of age.
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A randomized trial of glial-derived neurotrophic factor directly placed into the putamen did not show a statistically significant improvement or the signs and symptoms of PD.