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Associate Professor of Neurology and Neuroscience, Weill Medical College, Cornell University. Dr. Gouras reports no financial relationship relevant to this field of study.
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A single, high-dose treatment of cyclophosphamide stabilized or improved function in multiple sclerosis patients with moderate to severe disease that did not respond to prior trials of immunomodulatory or immunosuppressive drugs.
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This randomized, double-blind, placebo-controlled study showed that standard hormone replacement therapy using Prempro can increase seizure frequency in postmenopausal women with epilepsy in a dose-related manner.
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The stroke and death rates at one and 6 months were lower in patients with symptomatic carotid stenosis (> 60%) treated with endarterectomy versus stenting.
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In response to several high-profile drug misadventures including the rofecoxib (Vioxx®) withdrawal from the market, the FDA's Center for Drug Evaluation and Research (CDER) asked the Institute of Medicine (IOM) to assess the drug safety system in the United States.
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Camptocormia in PD is an extreme forward flexion of the spine, and has many characteristics of an axial action dystonia. The contribution of myopathy in muscles responsible for trunk extension has yet to be determined, and may be secondary to the dystonia itself.
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Patients with transient ischemic attacks should usually be admitted to the hospital and receive rapid evaluation and treatment.
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Subacute encephalopathy associated with thyroid antibodies and a history of autoimmune thyroid disease may respond dramatically to high-dose corticosteroid therapy.