Neurology Alert
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Ibudilast Shows Promise for the Treatment of Progressive MS
A Phase II trial of ibudilast in progressive multiple sclerosis demonstrated a decreased rate of brain atrophy when compared to placebo.
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Steroid Treatment Regimens for Chronic Inflammatory Demyelinating Polyneuropathy
In the United States, first-line treatment for chronic inflammatory demyelinating polyneuropathy (CIDP) is intravenous immunoglobulin (IVIG). Authors of this retrospective survey from Europe found that corticosteroid treatment had similar efficacy as IVIG and should be considered as first-line therapy for CIDP.
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Dual Antiplatelet Therapy for Acute Ischemic Stroke and TIA
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Treatment of Chronic Subdural Hematoma With Atorvastatin
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Atrial Flutter, Atrial Fibrillation, and Ischemic Stroke
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Recanalization Treatment in Pediatric Arterial Ischemic Stroke
In a population-based study from Switzerland, the authors found that recanalization treatment (intravenous thrombolysis or endovascular treatment) overall was safe without significant side effects or increased mortality compared to standard care.
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Hypercapnic Acidosis and Clinical Outcomes in Patients With Acute Brain Injury
In this multicenter retrospective study, hypercapnic acidosis was associated with worse clinical outcomes in mechanically ventilated patients with acute brain injury.
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Unilateral Scapular Winging
Scapular winging is an occasional finding on a neurological examination, rarely a chief complaint, and usually is caused by long thoracic nerve or spinal accessory nerve lesions.
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Initial Management of Patients With Medication-overuse Headache
As part of a randomized treatment trial for medication-overuse headache, a simple protocol that provided early advice on stopping excessive medications was effective in one-third of patients, even before any prophylactic medications were started.
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Which Is Better for Nonconvulsive Seizures: Lacosamide or Fosphenytoin?
Intravenous lacosamide was found to be noninferior to fosphenytoin in the treatment of nonconvulsive seizures in a prospective, multicenter, randomized clinical trial.