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The diagnosis of amyotrophic lateral sclerosis (ALS) at an early stage can be difficult. It is desirable to have an accurate diagnostic test due to the prognosis of the illness, as well as the potential ability to treat patients earlier.
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New alternative anticoagulants now exist that may be equally efficacious as warfarin and allow a more convenient fixed dosing schedule with a superior safety profile.
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In this randomized, placebo-controlled trial, 667 patients with stable advanced multiple sclerosis were assigned to 1 of 3 groups: oral cannabis, oral tetrahydrocannabinol, or placebo.
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Thirty-three consecutive patients with l3 or l4 radiculopathy were compared to 19 controls of comparable age to determine the best method for detecting quadriceps weakness in the office setting.
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Relying on careful monitoring to reduce the risk of toxicity, Ritchie and colleagues carried out a 36-week phase II test of the efficacy of clioquinol in reducing plasma beta-amyloid levels and slowing cognitive decline in patients with moderately severe Alzheimer's disease.
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In this elegant study, Seif and colleagues asked a simple question: does DBS alter urodynamic parameters in patients with Parkinson's disease?
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Benbadis and associates reviewed the medication history of patients with EEG-confirmed idiopathic generalized epilepsy.
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Fifty-one consecutive hepatitis c patients with neuropathy were evaluated to determine whether, and by what mechanism, cryoglobulinemia was associated with peripheral neuropathy.
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The availability of comprehensive records of public health in Scandinavian countries is a major advantage in working out epidemiological studies. The present study of Swedish twins including many older than 80 now suggests that the genetic component of AD may be less than previously thought.
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The prospects for therapy in Huntingtons disease are rapidly improving. Another potential treatment is to use striatal neural grafts.