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These studies provide additional data about the higher risk of relapse, and the greater potential for progression of disability following childbirth.
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It seems prudent to strongly consider use of melatonin in our cognitively delayed patients with disordered sleep, but to monitor those with epilepsy very closely for exacerbation, and withdraw the drug.
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The hundreds of presentations at this meeting provided encouraging evidence that existing Alzheimers therapies may have greater benefits than first realized, and that a new generation of potential disease-modifying therapies for AD may be on the way.
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The means by which prions cause neuropathologic damage remains to be established.
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The MATCH data provide quite strong evidence that the clopidogrel-aspirin combination is a less favorable option than previously thought, but its use may not be completely contraindicated.
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Current clinical trial evidence favors the use of aspirin or clopidogrel as first-line agents for the majority of patients with vascular disease.
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This condition preferentially affects large myelinated fibers of the posterior roots, may respond favorably to treatment, and may be a restricted form of chronic inflammatory demyelinating polyradiculoneuropathy.
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The mortality associated with bacterial meningitis remains high, and the strongest risk factors for an unfavorable outcome are those that are indicative of systemic compromise, a low level of consciousness, and infection with S. pneumoniae.
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These results demonstrate a major role of carotid thrombosis and inflammation in ischemic stroke in patients affected by carotid atherosclerotic disease.