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Practice parameters from the aan are strategies for patient management that assist physicians in clinical decision-making. These recommendations are derived from a thorough review that not only summarizes the available evidence-based medicine but, more importantly, assesses the quality of the data being reviewed.
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Like its cousin selegiline, rasagiline is a selective irreversible inhibitor of monoamine oxidase type B. Rasagiline has been shown to improve the motor and cognitive signs of experimental parkinsonism, and preliminary studies have demonstrated that the compound is more potent than selegiline.
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According to the pdr,1 16% of patients using sildenafil in clinical trials reported headache compared with only 4% of controls. Kruuse and associates studied the effect of sildenafil use apart from sexual activity in 12 patients with a history of migraine without an aura.
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Several lines of evidence suggest that ace inhibition and/or angiotensin receptor blockade can be effective for migraine prevention. Lisinopril has already been shown to reduce migraine headache.
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Retrospective review of needle emg findings on 45 patients studied during a 20-year period, with surgically verified compression of a single lumbosacral nerve root, was undertaken to determine the accuracy of traditional myotomal charts used to localize nerve root involvement.
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Among patients with plasma cell dyscrasias and polyneuropathy, most have monoclonal gammopathy of undetermined significance (MGUS), of which 50% are IgM in type. Most of these demonstrate activity against myelin-associated glycoprotein (MAG).
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Disorders of memory are frequently studied, but exceptional recall abilities have been the subject of relatively few investigations. In an effort to understand the neural basis of superior recall,
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The Centers for Disease Control and Prevention published Smallpox Vaccination and Adverse ReactionsGuidance for Clinicians in the Jan. 24th edition of Morbidity and Mortality Weekly Report. The guidance is a thorough review of the smallpox vaccine with a well-illustrated compendium of complications.
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Intravenous immunoglobulin (IVIG) is safe and effective therapy for acute exacerbations of myasthenia gravis (MG), myasthenic crisis, and for optimizing patients conditions in preparation for thymectomy. Its role in the long-term management of MG remains to be defined.
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Among patients with coronary artery disease, HMG CoA reductase inhibitors (statins) are a mainstay of therapy. These drugs have also become widely prescribed with a low threshold to patients with elevated cholesterol and even minimal cardiac risk factors.
