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The therapeutic response to indomethacin is the most reliable differential diagnostic criterion for PH vs CH.
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Once-daily rasagiline reduces mean daily off-time and improves symptoms of Parkinsons disease in levodopa-treated patients with motor fluctuations, an effect similar to that of entacapone.
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SNRIs may be performed safely with only minor side effects to be expected
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IgG from all narcolepsy patients significantly enhanced bladder contractile responses to the muscarinic agonist carbachol and to neuronally released acetylcholine compared with control IgG (P < 0.0001), whereas contraction of the sympathetically innervated vas deferens was unaltered.
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In SOD1(G93A) transgenic mice, a model for familial ALS, intraspinal injection of a lentiviral vector that produces RNAi-mediated silencing of SOD1 substantially retards both the onset and the progression rate of the disease.
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Researchers from Sweden performed a meta-analysis of 9 randomized, controlled trials that looked at the effectiveness of atenolol on cardiovascular morbidity and mortality in patients with hypertension.
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The present findings raise the possibility that new effective therapies may be developed for CMT2A, which target the underlying pathophysiology.
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There is an increase in mortality with methylprednisolone in the 2 weeks after head injury. The cause of the rise in risk of death within 2 weeks is unclear.
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This condition preferentially affects large myelinated fibers of the posterior roots, may respond favorably to treatment, and may be a restricted form of chronic inflammatory demyelinating polyradiculoneuropathy.