Lipids
RSSArticles
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The Effect of Age on Cholesterol-Lowering Therapy
Investigators analyzed data on the effect of age on cardiovascular (CV) outcomes and LDL cholesterol-lowering by alirocumab vs. placebo in recent acute coronary syndrome patients. They found alirocumab can lower the rate of CV events regardless of age — and produce more absolute benefit with age.
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A New Treatment for Refractory Hyperlipidemia
In patients with familial hypercholesterolemia who are not at target LDL cholesterol levels on maximum-tolerated doses of statins and PCSK9 inhibitors, evinacumab, which inhibits angiopoietin-like 3, reduces LDL by more than 50% at the highest doses with few side effects requiring drug discontinuation vs. placebo.
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The Effect of Age on Cholesterol-Lowering Therapy
Investigators analyzed data on the effect of age on cardiovascular (CV) outcomes and LDL cholesterol-lowering by alirocumab vs. placebo in recent acute coronary syndrome patients. They found alirocumab can lower the rate of CV events regardless of age — and produce increasing absolute benefit with age.
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Scientists Observe Possible Relationship Between Autism Subtype, Cholesterol Levels
Results of this investigation confirm the challenges of understanding autism, its subtypes, and the arcane causes.
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Predicting the Response to CRT-D Therapy
This paper gives the results of a substudy from the Multicenter Automatic Defibrillator Implantation Trial with Cardiac Resynchronization Therapy (MADIT-CRT) trial. -
Indication for ICDs in Arrhythmogenic RV Cardiomyopathy Patients
Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is an uncommon condition with a wide spectrum of possible clinical presentations. Implantable defibrillators (ICDs) are standard therapy for treating ARVD/C patients who present with sustained ventricular tachycardia (VT) or cardiac arrest. -
Clinical Briefs in Primary Care Supplement
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Pharmacology Watch
New recommendations for HPV vaccine; guidelines for treatment of essential tremor; updates on smoking cessation drugs; and FDA actions. -
Laser Pacemaker Lead Extraction in Octogenarians
In this paper, Rodriguez and his colleagues from the Department of Cardiothoracic Surgery at the University of Miami report their experience with laser-assisted cardiac rhythm device lead extraction in a large group of patients. -
BNP in Chronic Aortic Regurgitation
The most appropriate time to intervene in asymptomatic patients with chronic severe aortic regurgitation is controversial. Since brain natriuretic peptide (BNP) is released by the heart in response to increased wall stress, it has been proposed as a biomarker of the time to intervene in chronic valvular regurgitation patients.