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  • Riata ICD Lead Failures

    The Riata and Riata ST ICD leads manufactured by St. Jude Medical have recently come under increased scrutiny because of the observation that the conductor cables could extrude from the outer insulation.
  • Perioperative Risk in Patients with Coronary Stents

    It is well known that the risk of perioperative major adverse cardiac events (MACE) is high in patients with coronary stents, especially early after stent implantation.
  • Oral Anticoagulants During Pregnancy

    Newer bileaflet mechanical heart valves require lower doses of oral anticoagulants to avoid valve thrombosis and embolism genesis. However, little is known about the safety of low-dose regimens in pregnant women who have a hypercoagulable state, yet warfarin embryopathy is known to be dose related.
  • Clinical Briefs in Primary Care Supplement

  • Pharmacology Watch

    Drug shortages; metformin and cancer prevention; migraine prevention guidelines; and FDA actions.
  • New Cardiomyopathy

    These investigators from Australia present a case of isolated left ventricular (LV) apical hypoplasia with fatty infiltration confirmed by CT and MRI. The left anterior descending artery was small and truncated early on angiography. Echocardiography showed a large banana-shaped right ventricle (RV) that wrapped around the apex of the hypocontractile truncated LV. Also there was apical papillary muscle insertion.
  • Risk of Sudden Cardiac Death with Azithromycin

    In this paper, the authors performed a pharmacoepidemiologic study on the relationship between azithromycin, a frequently used broad-spectrum macrolide antibiotic, and cardiovascular death. The authors analyzed data from the Tennessee Medicaid program. This database provides information on medical care encounters and dates and causes of death and is linked to death certificates and hospital discharge data.
  • Pharmacology Watch

    Azithromycin and cardiac risk; warfarin and heart failure; aspirin and VTE; effectiveness of long-acting contraceptives; and FDA actions.
  • New Insights into Atrial Fibrillation Ablation

    This interesting study examined a new technique for exploring the mechanism(s) for atrial fibrillation (AF). Patients scheduled for catheter ablation of paroxysmal or persistent AF were recruited for the study. Antiarrhythmic drugs were stopped before the study was performed.
  • Clinical Briefs in Primary Care Supplement