Internal Review Boards
RSSArticles
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Patients Share Preferences About Data Privacy
Most want security and accountability, are concerned about who can access their information and for what purposes.
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Participant Distress Is Concern for IRBs Reviewing Child Maltreatment Studies
Surveys measuring prevalence of child maltreatment are important knowledge, but IRBs might overestimate the risk to participants.
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Unique Challenges for IRBs Evaluating Radiation Oncology Study Protocols
There may be few if any radiation oncology investigators at some institutions, and radiation therapy involves rapidly advancing technology. In light of this, IRBs might lack the necessary expertise to review these studies.
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Critical Care Nurse Researchers Must Know IRB Process
Many critical care nurses are involved in study recruitment. Lack of basic knowledge on how IRBs work can hinder this process.
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The Reproducibility Crisis in Clinical Trial Research
Theoretically, a researcher should be able to reproduce any clinical trial and see the same or similar findings. Yet the long-standing “reproducibility crisis” in science persists, resulting in a surge of new analyses and recommendations.
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IRBs May Need to Seek Outside Expertise; More Data Are Needed
It is impossible for any IRB to claim an exhaustive range of methodological and disciplinary expertise within their membership. Without the right expertise, the quality of IRB review comes into question. But for a variety of reasons, IRBs may not be taking advantage of the option to use outside experts.
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Greater Awareness of Reporting Bias on Antidepressants, Yet Problem Persists
An investigator who was part of a landmark study on the efficacy of antidepressants recently revisited reporting transparency in this area of research.
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Ethical Concerns Persist Over Reporting Bias in Clinical Trials
Several changes could be made, including enforcement of penalties for delays in reporting trial results; journals prioritizing accuracy between published results and the original study protocols; and mitigating the problem of selective registration, publication, and reporting on ClinicalTrials.gov.
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Many Parkinson’s Research Participants Cannot Recall Study Risks
Rather than consenting an individual in the office during the presurgical visit, at a time when the patient was already receiving a large amount of information, the outreach could be conducted by phone later. This would give the subject time to carefully review the study materials.
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Uncertainties on Future Use of Study Participants’ Data
Generally, the informed consent process needs improvement, particularly when it comes to explaining to participants what data will be used and how. Responsible data-sharing rests on making quality data accessible to authorized researchers to meaningfully advance science while respecting participant values.