Internal Medicine
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The Enduring Enigma of Vitamin D Supplementation
Murky federal panel recommendation, ongoing research likely to keep debate going for some time to come.
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FDA Approves AI Tool to Help Detect Colon Cancer
Machine learning gives clinicians another tool while trying to detect troubling signs during routine screening.
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Rapid Intermittent Bolus of Hypertonic Saline May Be a Better Way to Correct Symptomatic Hyponatremia
In this randomized clinical trial, hypertonic saline given via rapid intermittent bolus therapy was as effective and safe as slow continuous infusion, and was associated with a lower rate of recorrecting treatment and higher efficacy in achieving goal sodium within one hour.
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Using Procalcitonin to Limit Antibiotic Treatment for Sepsis Reduces Infection-Related Adverse Events
By shortening the duration of antibiotic therapy, a procalcitonin-guided protocol decreased the rate of infection-associated adverse effects, decreased costs, and reduced mortality in patient with sepsis.
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Post-COVID-19: The Crisis After the Crisis
Critical care physicians have the opportunity to optimize long-term function and quality of life for COVID-19 survivors. It is paramount to prevent, recognize, and treat post-COVID-19 symptoms.
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Dasiglucagon Injection (Zegalogue)
Dasiglucagon should be prescribed to treat severe hypoglycemia in pediatric and adult patients (≥ age 6 years).
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Herpes Zoster Vaccine: Effective but Underused
The adjuvanted recombinant herpes zoster vaccine is highly effective in practice, but it is vastly underused.
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Antibiotics: Less Is Better, Sometimes
In England, and likely in many other areas of the world, antibiotics are given for longer than necessary. Excessively long durations of antibiotic use do not help patients and risk leading to more resistant infections.
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Is Empagliflozin Safe in Combination with a Neprilysin Inhibitor for Heart Failure?
A prespecified subgroup analysis of heart failure patients with reduced ejection fraction who were on neprilysin inhibitors before empagliflozin was administered (vs. those not on neprilysin inhibitors) showed the reduction in mortality and hospital admissions for heart failure was not attenuated by concurrent neprilysin use.
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Accounting for Patient Preference, Cardiovascular Disease Risk in Statin Therapy
Researchers weighed patient preferences and risks regarding statin therapy after reviewing 10-year atherosclerotic cardiovascular disease risk scores.