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Biomarkers have become an important tool for the early recognition and prognostication of acute kidney injury. In the last few years, several biomarkers have emerged that have shown promising results in large-scale clinical studies.
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Finerenone can be prescribed to lower the risk of sustained estimated glomerular filtration rate decline, cardiovascular death, non-fatal myocardial infarction, end-stage kidney disease, and hospitalization from heart failure in adults with chronic kidney disease associated with type 2 diabetes.
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In this retrospective, cross-sectional study of men, both sleepwalking and rapid eye movement sleep behavior disorder were associated with the development of Parkinson’s disease.
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There is a significant increase in dementia risk associated with the use of anticholinergic medications for three months or longer.
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Saccharomyces boulardii is a probiotic yeast that may cause fungemia and other fungal infections.
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The authors review chromium, cinnamon, fenugreek, garlic, and Gymnema sylvestre as complementary and alternative medicine supplements for managing type 2 diabetes.
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Patients with three-vessel or left main coronary artery disease randomized to coronary bypass surgery vs. percutaneous therapy on optimal medical therapy at five years with three or four of the recommended drugs recorded a lower 10-year all-cause mortality rate vs. those on ≤ 2 drugs.
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A tailored, progressive physical rehabilitation program started in the hospital and continued for three months in older, relatively frail acute heart failure admissions resulted in significantly improved physical function vs. usual care but did not reduce six-month readmission rates.
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In this trial of cerebral protection in transcatheter aortic valve replacement, the TriGUARD device was safe vs. historical controls, but failed to meet its primary efficacy endpoint.
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An analysis demonstrated an inverse association of coffee consumption and cardiac arrhythmias, which was not altered by genetic variations in caffeine metabolism, age, or sex.