Internal Medicine
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Updated Sexually Transmitted Infection Guidelines
The Centers for Disease Control and Prevention has updated their recommendations for the treatment of several sexually transmitted infections, including gonorrhea, trichomoniasis, bacterial vaginosis, pelvic inflammatory disease, and those due to Chlamydia trachomatis and Mycoplasma genitalium.
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Neutrophil Extracellular Traps and COVID-19
Neutrophil extracellular traps (NETs) contribute to immune-mediated inflammation and thrombosis. Donor neutrophils were stimulated with plasma from patients hospitalized with COVID-19. R406 (metabolically active component of fostamatinib) abrogated release of NETs in vitro.
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Children Hospitalized with SARS-CoV-2
Two recently published studies give a clear, consistent finding: About three-fourths of children hospitalized with SARS-CoV-2 do not have severe COVID-19-related illness but are merely identified as infected when subjected to screening tests. Surveys reporting the number or incidence of SARS-CoV-2-infected hospitalized children likely overestimate the actual burden of disease.
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Emotional Eating and Obesity
This review of research regarding the link between emotional eating (eating in response to unpleasant emotions) and obesity in adults suggested several factors that contribute to emotional eating and methods for patients to reduce it.
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The Safety and Efficacy of Common Herbal and Dietary Supplements in Patients with Type 2 Diabetes Mellitus: Part 3
While part 1 of this literature review series discussed Aloe vera and alpha-lipoic acid, part 2 of this series presented information on chromium, cinnamon, fenugreek, garlic, and Gymnema sylvestre. This last part provides study findings relating to ginseng, magnesium, nopal, and psyllium.
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Researchers Find Lower Amyloid Levels in Patients on Blood Sugar Control Drug
An investigation reveals an interesting trait among those taking a common diabetes management solution. -
Recognizing Personality Disorders in Patients Presenting to the Primary Care Provider
Often not well understood by the medical community and surrounded in stigma, patients with personality disorders frequently are labeled difficult. Understanding that the behaviors responsible for this label may be the result of a personality disorder allows the provider to adopt a more nuanced approach to treatment.
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Medical Groups Back Youth Right to Consent
National organizations filed amicus briefs in two federal cases centered on a law enacted in Washington, DC. -
Dexmedetomidine and Temperature Elevation: Is the Link Important?
In this post hoc analysis of the SPICE III trial, a greater percentage of patients receiving dexmedetomidine had temperatures greater than or equal to 38.3ºC and 39.0ºC compared to usual care. Although there was a significant dose response relationship between dexmedetomidine received and increase in temperature, there was no difference between groups in terms of paracetamol, antimicrobial, neuromuscular blocker, neuroleptic drug use, blood cultures performed, or initiation of renal replacement therapy. -
Lung Protective Ventilation in ARDS: What Is the Best Strategy?
Using newer methodology in network meta-analysis to compare various protective mechanical ventilation strategies, the authors concluded that a low tidal volume strategy combined with prone ventilation was associated with the greatest risk reduction in mortality for moderate to severe acute respiratory distress syndrome.