Internal Medicine
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Slow, Steady, and Synchronized Wins the Race
In patients with atrial fibrillation and heart failure, definitive rate control via atrioventricular junction ablation and biventricular pacing resulted in a significant reduction in all-cause mortality vs. pharmacologic rate control.
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Screen Older Heart Failure Patients for Transthyretin Cardiac Amyloidosis
A screening study of heart failure patients ≥ age 60 years, left ventricular ejection fraction ≥ 40%, and left ventricle wall thickness ≥ 12 mm revealed 6.3% prevalence of transthyretin cardiac amyloidosis, a highly treatable disease.
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For Most Patients on Dialysis, Religious/Spiritual Beliefs Are Important
Researchers surveyed 937 patients receiving dialysis at 31 facilities in Nashville and Seattle from 2015 to 2018. Those for whom religious or spiritual beliefs were more important were more likely to favor a shared decision-making role, more likely to favor resuscitation and mechanical ventilation, and less likely to have considered stopping dialysis.
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Is This Ventricular Tachycardia?
The ECG in the figure was obtained from an elderly man with chest pain and shortness of breath. Is the rhythm ventricular tachycardia?
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Insulin Glargine-yfgn Injection (Semglee)
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Anticoagulation Plus Antiplatelet Therapy in Chronic Atherosclerosis
An analysis of the COMPASS trial for the secondary endpoint of mortality showed the combination of low-dose rivaroxaban and aspirin significantly lowered the all-cause mortality rate vs. low-dose aspirin alone.
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No Harm in a Morning Cup of Joe
Habitual coffee consumption was inversely associated with a lower risk of cardiac arrythmia.
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Statins, Cognitive Decline, and Dementia
An analysis of the ASPREE database showed that with almost five years of follow-up, statins are not associated with cognitive decline or dementia in a large group of elderly subjects in whom multiple tests of cognition were performed serially.
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COVID-19 Vaccination: The Heart of the Matter
The occurrence of myocarditis after receipt of COVID-19 vaccines is most frequent in young men and generally benign, with rapid resolution only through supportive care. Careful analysis indicates the benefit of vaccination outweighs the risk in all groups for whom the vaccine is recommended.
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Jury Still Out on Convalescent Plasma
One year after the FDA issued an emergency use authorization, investigators are struggling to draw firm conclusions about the efficacy of this solution against COVID-19.