Internal Medicine
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Meat Consumption Associated with Less Anxiety and Depression
A meta-analysis of 20 studies showed meat consumption resulted in better mental health, with less anxiety and depression vs. meat abstinence.
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Incidence, Prevalence, and Long-Term Consequences of Small Fiber Neuropathy
Small fiber neuropathy (SFN), a subtype of peripheral neuropathy characterized by painful distal neuropathic pain and autonomic symptoms, is increasing in incidence. SFN associated with diabetes and other causes is more likely to progress to large-fiber polyneuropathy and have faster deterioration and higher disability compared to slow progression with idiopathic SFN. Glucose impairment, obesity, and elevated triglycerides are modifiable risk factors of idiopathic SFN. Although major disability and neurologic impairment are uncommon in this slowly progressive condition, higher mortality and cardiovascular events are noted in patients with SFN.
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Recognizing Stroke Mimics: A Guide for Primary Care
Acute ischemic stroke is a common and significant cause of mortality and morbidity in the United States, ranking fifth among all causes of death. However, timely recognition and treatment is complicated by the fact that there are multiple conditions that mimic acute ischemic stroke. A comprehensive review suggested that approximately 74% of patients presenting with apparent acute stroke symptoms ultimately were diagnosed with stroke, thus indicating that 26% of patients had their symptoms produced by “stroke mimics.” Therefore, prompt diagnosis is complicated by a multitude of stroke mimic etiologies, including structural intracranial abnormalities, infection, syncope, vertigo, seizure, and migraine patterns, as well as underlying psychiatric causes and demyelinating diseases.
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AAN Offers Ethical Guidance on Alzheimer’s Drug
Neurology experts issue caution on costs, side effects regarding the approved-but-controversial Aduhelm.
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Infectious Disease Alert Updates
Risk of COVID-19 During Air Travel; Symptoms Post-COVID: Loss of Taste in One in Seven; Effectiveness of Cloth and Surgical Masks Against SARS-CoV-2.
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Missing the Diagnosis of Congenital Syphilis
The diagnosis of congenital syphilis was delayed until the post-neonatal period in 2.2% of infants born in the United States from 2014-2018.
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An Outbreak of Injection Site Mycobacterium porcinum Infections After Vaccination in the Workplace
Vaccine (non-COVID-19) contamination as a result of improper handling led to injection site infections due to Mycobacterium porcinum, a rapid growing non-tuberculous mycobacterium present in the environment.
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Fluvoxamine Reduces the Risk for Hospitalization from COVID-19
A randomized, placebo-controlled trial found fluvoxamine (100 mg twice a day for 10 days) reduced the risk for hospitalization among high-risk outpatients diagnosed with COVID-19.
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Melioidosis in the United States
Four cases of melioidosis in four states occurred and at least one was traced to a contaminated commercial aromatherapy product.
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Pediatric Pneumonia — Diagnostic and Therapeutic Stewardship
A randomized, multicentered trial in the United Kingdom and Ireland showed children receiving amoxicillin for community-acquired pneumonia perform similarly well with lower dose (35-50 mg/kg/day vs. 75-90 mg/kg/day) and shorter duration (three vs. seven days) treatments.