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After initial trials showed a mortality benefit from the use of insulin drips and tight glucose control in the ICU, subsequent studies have shown mixed results and, in some cases, increased mortality and episodes of hypoglycemia.
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Delirium is a common and serious disorder in ICU patients, with up to 87% incidence in some ICU populations. Studies have shown that delirium is associated with higher costs and complication rates, namely increased ventilator days and longer hospital stays.
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Peek and colleagues have recently published the long-awaited and much-discussed results of the CESAR trial (Conventional ventilatory support vs Extracorporeal membrane oxygenation [ECMO] for Severe Adult Respiratory failure), a British study that has been underway for nearly a decade.
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The hand clapping test is a quick and reliable way to screen for parietal lobe neglect syndrome.
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Biomarkers in the cerebrospinal fluid may help in the early diagnosis of Alzheimer's disease.
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Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis has been recognized in children as young as 23 months as well as adolescents.
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Elevated levels of a specific organochlorine pesticide are associated with Parkinson's disease.
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Transcranial magnetic stimulation was shown to have benefit during stroke rehabilitation therapy, in this randomized, controlled clinical trial.
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In preliminary, open-label trials, rituximab shows promise as a treatment for IgM-associated neuropathy.