Internal Medicine
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Using Breathing Techniques for Exertion and Anxiety During COVID Lockdowns
In a small prospective study comparing four breathing techniques, the maximum statistically significant effect on reduced perceived exertion during breath-holding is associated with a yoga breathing method called anulom vilom pranayama (alternate nostril breathing).
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Missed STEMI Time Frames Will Complicate ED Malpractice Defense
Recently updated guidelines drive home the urgency of early ECG testing and rapid treatment.
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Is Physical Activity Associated with Mortality Risk in Parkinson’s Disease?
In individuals with Parkinson’s disease (PD), physical activity (PA) at all intensities is associated with reduced all-cause mortality, with the greatest reduction seen in individuals who maintained PA before and after PD diagnosis.
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The Effect of Disease-Modifying Therapies for Multiple Sclerosis on the Immune Responses to COVID-19 Vaccination
An analysis of a large group of patients with multiple sclerosis taking various disease-modifying therapies showed that the response to COVID-19 vaccination was not uniform across the therapies. Patients taking anti-CD20 therapies and fingolimod had attenuated responses to vaccines.
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Diet and the Risk of Dementia
Specific dietary patterns, such as the Mediterranean-style diet, have been shown to promote brain health, mitigate neuro-inflammation, and reduce the risk of dementia. This prospective cohort study demonstrated an association between a high inflammatory potential diet and increased risk for incident dementia.
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Acute Muscle Weakness in Children: Acute Flaccid Myelitis or Guillain-Barré Syndrome?
Compared to children with Guillain-Barré syndrome, children with acute flaccid myelitis have a more rapid presentation to nadir of weakness, fewer sensory abnormalities, and an inflammatory spinal fluid early in the course.
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The Effect of Epilepsy on Patients with Brain Tumors
Cancer cells form direct synapses with neurons, whose electrical activity stimulates brain tumor growth. Accumulating evidence suggests that epilepsy enhances the proliferation of malignant brain tumors and that improved management of epilepsy may reduce morbidity and mortality in these patients.
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Recognizing and Treating Substance Use Disorders
Results from the 2019 National Survey on Drug Use and Health reveal 20.3 million people living in the United States have an addiction or substance use disorder (SUD). Geographic and financial barriers, as well as bias and stigma, work together to present formidable roadblocks for patients with SUD looking for direction. The primary care provider (PCP) may be the only healthcare contact for many of these patients. With expertise in understanding management of other complex, chronic disorders and experience in implementing an integrated, individualized treatment plan, the PCP has the background to take the lead in managing patients with SUD.
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Infectious Disease Alert Updates
Mandating COVID-19 Vaccination for Healthcare Workers — Revisited; SARS-CoV-2 as a North American Zoonosis; VIRSTA vs. PREDICT in Predicting Endocarditis
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Herpes Simplex Virus 2 Meningitis in Adults
The incidence of herpes simplex virus 2 meningitis in adults in Denmark over a six-year period was 0.7/100,000 population per year, with 91% of cases occurring in the absence of immunocompromise. Neurocognitive or neuropsychiatric symptoms persisted for as long as six months in approximately one-fifth of cases.