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In June 2009, the advisors of the U.S. Food and Drug Administration recommended lowering the maximum dose of over-the counter acetaminophen, which is the key ingredient in such popular products such as Tylenol and Excedrin. The advisors were concerned that severe liver damage and even death can result from excessive ingestion of acetaminophen, which many consumers consider to be easier on the stomach than other medications and safe.
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Restless Legs Syndrome (RLS) was present in 50% of patients with Friedreich's ataxia (FA), a disorder of intramitochondrial iron accumulation. This study suggests that RLS treatment will potentially help the sleep disorder in appropriately screened FA patients.
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Anosognosia is an important, but often neglected, part of the neurological examination in a patient with stroke.
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VEGF is elevated in the serum and plays a role in the pathogenesis of neuropathies associated with monoclonal gammopathies.
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Statins and liver function; dosing timing for thyroxine; rivaroxaban for VTE, DVT, and stroke; echinacea and the common cold; and FDA actions.
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Dopamine transporter deficiency (DAT) is a rare inherited disorder that causes a Parkinsonian syndrome in infants and young children.
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Thalamic deep brain stimulation improves ataxia in subjects with essential tremor at therapeutic stimulation parameters, and worsens ataxia at supra-therapeutic parameters.