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In this issue: Anticholinergic drugs for COPD; pioglitazone for diabetes prevention; insulin degludec in Phase 3 trials; and FDA Actions.
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Although previous studies have suggested that hypocalcemia, a common problem in critical illness, is associated with increased mortality in ICU patients, and correction of hypocalcemia has been advocated to prevent neurologic and cardiovascular complications, the literature is still unclear as to the precise relationship between abnormal calcium levels both hypo- and hypercalcemia and ICU outcomes.
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Chronically critically ill patients are projected to increase in number over the next 10 years.
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The ECG above was obtained in the office from a 47-year-old woman who said she had "heart problems" that resulted in hospitalization the month before.
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The action to control cardiovascu-lar risk in diabetes (ACCORD) study is really three studies in one, providing information about blood pressure, glucose, and triglyceride treatment in high-risk diabetic patients.
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The FDA has approved the first new treatment for systemic lupus erythematosus (SLE) since 1955 when hydroxychloroquine and corticosteroids were approved. Belimumab is a recombinant human IgG1l monoclonal antibody specific for soluble human B lymphocyte stimulator protein (BLyS).
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This study concluded that subjects without a known history of any cardiovascular disease who demonstrated ventricular premature complexes on a 2-minute rhythm strip are significantly more likely to die from sudden cardiac death and the effect appears to be additive when atrial premature complexes occur concurrently.
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Women who drink little or no coffee appear to be at an increased risk of stroke compared with those who drink moderate amounts of coffee.