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Progressive multifocal leukoencephalopathy is a rare complication of immunosupression in patients who undergo organ transplantation, with a high death rate.
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Cases of autopsy-proven corticobasal degeneration examined in a U.S. academic center presented with frontal-predominant behavioral or cognitive deficits, with a movement disorder following later in the majority.
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Two recent clinical trials, rocket af and aristotle, have added two new direct thrombin inhibitors, in addition to dabigatran (RE-LY), to our armamentarium to prevent stroke in patients with atrial fibrillation.
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Medication poisonings in children; rosuvastatin vs atorvastatin for atherosclerosis; saw palmetto for prostate symptoms; using atypical antipsychotics for off-label indications in adults; and FDA actions.
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Extracorporeal membrane oxygenation is associated with a high mortality and a high incidence of neurological complications including stroke, subarachnoid hemorrhage, and brain death.
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The benefits of cardiac rehabilitation following myocardial infarction (MI) are well known. However, whether these benefits are also seen in ambulant community-based patients who undergo percutaneous coronary intervention (PCI) is not known.
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Most (83%) patients/surrogates stated they preferred full code status but only 4% could identify the components of CPR; 16% stated preferences that differed with the medical record.
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Standard therapy for bacterial meningitis in children is probably overkill but it is risky to cut back in resource-rich countries.
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This randomized study of low-tidal-volume ventilation during and after cardiac surgery, in comparison to ventilation with tidal volumes of 10 mL/kg predicted body weight, showed no differences in median ventilation time but higher rates of extubation by 6 and 8 hours postoperatively and fewer reintubations in the low-tidal-volume group.