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Adding gabapentin to valacyclovir early in the treatment of acute herpes zoster may reduce the incidence of postherpetic neuralgia.
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Failed extubation is more likely to occur in elderly patients with underlying chronic cardiac or pulmonary disease, and patients in whom it occurs have substantially worse clinical outcomes than those who do not require reintubation.
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Clopidogrel therapy is indicated for many patients with cardiovascular disease, particularly those who have had percutaneous coronary intervention (PCI).
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Since there is a lack of prospective data on the frequency of which constrictive pericarditis (CP) develops after acute pericarditis (AP), this group of investigators from Torino, Italy, conducted such a study.
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The FDA has approved the first fixed-dose combination product for the treatment of type 2 diabetes and hypercholesterolemia. This tablet combines a dipeptidyl peptidase-4 inhibitor (sitagliptin) and a HMG-CoA reductase inhibitor (simvastatin).
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In a large randomized trial of healthy men, dietary supplementation with vitamin E (400 IU/day) significantly increased the risk of prostate cancer.
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In a large community-based cohort of older women, those who self-reported use of multivitamins, vitamin B6, folate, iron, magnesium, zinc, and copper were more likely to die than those who do not. Calcium use, however, was associated with reduced risk.
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The presence of any observed hostility at baseline was associated with a two-fold increased risk of incident ischemic heart disease over a 10-year period of observation.