Internal Medicine
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Predictors of Refractory Status Epilepticus
In a combined derivation and validation study, three independent risk factors for refractory status epilepticus were identified — acute symptomatic cause for seizures, stupor or coma, and a low serum albumin < 35 g/L. -
How Common Are Neuromuscular Disorders?
Synopsis: Although many specific neuromuscular disorders are rare, in aggregate, these all add up to a large number, roughly twice as common as multiple sclerosis, and about the same prevalence as Parkinson’s disease.
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Influenza, 2014-2015 — Something Old, Something New
As of early January, influenza activity had reached epidemic proportions in large parts of the United States, with many of those being affected despite prior vaccination.1 The occurrence of infection in vaccinated individuals is not unexpected since influenza vaccine efficacy is usually only approximately 60%.
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Does Your Patient Have a Central Venous Catheter?
Central venous catheters (CVCs) are essential to providing optimal care to many hospitalized patients.
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Neuroimaging Differences in Dyslexics: Chicken or Egg?
Neuroanatomical differences in primary sensory cortices may distinguish dyslexic individuals from non-dyslexic individuals, providing a potential biomarker for identifying adults who may be predisposed to developing atypical neurodegenerative disease. -
Take Me Out of the Ball Game: Acute Management and Long-term Consequences of Concussion in Childhood
The developing brain of a child may be particularly susceptible to injury from mild traumatic brain injury, such as a concussion. Recommending a longer period of strict rest after a concussion does not provide additional benefit when compared to consensus guidelines for care after a concussion in children and adolescents. However, in retired former NFL players, exposure to tackle football prior to age 12 is associated with executive dysfunction, memory impairment, and lower estimated verbal IQ later in life. -
Infectious Disease Alert Updates
The problem of diagnosing TB in children
How best to treat latent TB?
Transmission risk in smear-negative TB
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Antibiotics for Traveler’s Diarrhea?
Foreign travel is associated with travelers’ diarrhea and the intestinal acquisition of extended-spectrum beta lactamase-producing Enterobacteriaceae, especially when travel is to South Asia. The risk of acquisition of resistant flora was almost doubled when antibiotics were used to treat the episode of diarrhea.
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Ceftolozane/Tazobactam — Formulary Considerations
Information about ceftolozane/tazobactam
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Deworming Is Beneficial in HIV-infected Patients
988 HIV-infected pregnant women receiving ART in sub-Saharan Africa were treated with albendazole in a targeted or non-targeted fashion. Albendazole therapy was associated with favorable changes in hemoglobin levels, CD4 counts, and viral loads, particularly in patients with helminth infections.