Internal Medicine
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Pick Disease: Picking Away at the Pathology
The neuropathologic changes of Pick disease may sequentially progress through the brain in specified phases over time and may correlate with the progression of clinical symptoms.
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Thalamic Pain: Who Is Likely to Develop This Disorder?
In a careful anatomic and physiologic study of patients with thalamic stroke, the authors demonstrated that the combination of anterior pulvinar nucleus involvement with spinothalamic dysfunction predicts a “thalamic pain syndrome” with > 90% sensitivity.
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Peripheral Nerve Disorders After Cardiac Surgery
Following cardiac surgery, about 6% of patients will suffer a peripheral nerve injury, mostly due to compression, traction, or nerve ischemia. Proper patient positioning can prevent most of these injuries.
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Treatment of Acute Ischemic Stroke
MONOGRAPH: The faster definitive stroke treatment is administered, the better the outcomes. Unfortunately, most patients arrive too late.
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Apneic Oxygenation During Intubation for Respiratory Failure
Use of apneic oxygenation with a high-flow nasal cannula during endotracheal intubation for acute respiratory failure is no better at preventing arterial oxygen desaturation than usual care using pre-oxygenation.
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Does Acetaminophen Help Febrile Patients with Infection?
Scheduled intravenous acetaminophen lowers temperature but does not affect ICU-free days, mortality, length of stay, or adverse events in patients with sepsis.
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What is the Best Rate Control Agent for Patients with Sepsis and Atrial Fibrillation?
Beta-blockers may be associated with better outcomes in patients with sepsis and atrial fibrillation.
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Dyspnea and Asynchrony During Mechanical Ventilation
Breathing is the primal sensation of postnatal life, the disturbance of which produces the most profound sense of dread.
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Clinical Briefs
In this section: a better way to measure blood pressure; the magical powers of grapefruit juice; and yet another reason to stop smoking.
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Coagulation Factor IX (Recombinant), Albumin Fusion Protein
This product is indicated for on-demand control and prevention of bleeding episodes, perioperative management of bleeding, or routine prophylaxis to prevent or reduce the frequency of bleeding episodes in children and adults with hemophilia B (congenital factor IX deficiency).