Internal Medicine
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Clinical Significance of Mitral Annular Calcification
Researchers found mitral annular calcification to be uncommon, and few experienced associated moderate to severe mitral stenosis or regurgitation. However, the latter group recorded a high mortality rate over three years follow-up, which was significantly lower in those who underwent valve interventions, even when corrected for younger age, fewer comorbidities.
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Family Members of Critically Ill Patients with SARS-CoV-2 Pneumonia Have a High Burden of Symptoms of PTSD
This multicenter cohort study found a high incidence of post-traumatic stress disorder symptoms among family members of COVID-19 patients at three months after the index intensive care unit admission.
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Hot Trials from the European Society of Cardiology Annual Congress
Some highlights from two key studies presented in Barcelona, Spain, between Aug. 26 and Aug. 29, 2022, along with Dr. Crawford’s personal commentary on both.
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Where Are the P Waves?
The ECG in the figure was obtained from a previously healthy young woman with “palpitations.” How would one interpret this two-lead rhythm strip? Is there a conduction disorder?
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Bivalent COVID-19 Vaccine (Booster Dose)
The FDA has amended the emergency use authorizations of two leading COVID-19 vaccines. Now, these new bivalent formulations can be used as a single booster dose (after primary or booster vaccination).
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Prevalence of Urinary Incontinence Among Adult U.S. Women Has Increased
The updated prevalence of urinary incontinence using the National Health and Nutrition Examination Survey data is 60% in community-dwelling women, which is an increase from prior estimates.
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Understanding Statin-Related Muscle Pain and Cardiovascular Benefits
A review of large-scale, randomized, double-blind trials of statin therapy suggested statins are responsible for only a small excess of muscle pain symptoms in patients taking these drugs.
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Statins Plus Ezetimibe vs. Statins Alone
A comparison of rosuvastatin 10 mg/day plus ezetimibe (10 mg/day) to 20 mg/day of rosuvastatin alone showed non-inferiority in three-year major cardiovascular outcomes, with lower LDL cholesterol levels and fewer episodes of drug discontinuation or dose reductions in the combination therapy group.
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Poor Cardiovascular Health a Predictor for Premature Brain Aging
Worse cardiovascular health at age 36 years can predict worse brain aging and associated cognitive problems later in life.
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Epilepsy: The Hidden Side Effect of Bariatric Surgery
The benefits of weight loss procedures are numerous, but a recently published paper reveals a long-term side effect clinicians and patients should heed.