Internal Medicine
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Infectious Disease Alert Updates
Wee Bacterium Parasitizes Other Oral Bacteria; How Safe Is Your Honey?; Benefits of TB Screening Confirmed
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Can the Human Papillomavirus Vaccine Cure Cervical Dysplasia?
In this randomized, controlled trial, the HPV 16/18 vaccine did not hasten resolution of existing oncogenic HPV infections nor prevent persistent HPV 16/18 associated infection and cervical dysplasia recurrence after loop electrosurgical excisional procedure treatment.
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VRE and MRSA: Should We Stop Routine Contact Precautions?
The value of routine contact precautions for VRE and MRSA is strongly challenged.
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Empirical Antifungals in the ICU — Probably Not Helpful
Two hundred sixty non-neutropenic ICU patients with clinical evidence of sepsis receiving broad-spectrum antibiotics and known to be colonized by Candida species were randomized to micafungin for 14 days vs. placebo. Empirical micafungin therapy did not increase invasive fungal infection-free survival at 28 days.
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Cranberry Capsules Are Not Effective in Preventing Bacteriuria with Pyuria in Elderly Women in Nursing Homes
A randomized, double-blind, placebo-controlled trial found that giving cranberry capsules to elderly women residing in nursing homes did not result in any significant benefits, including no reduction in symptomatic urinary tract infections.
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Subacute Sclerosing Panencephalitis
Subacute sclerosing panencephalitis is a lethal complication of measles that is not as rare as previously believed.
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CDC Recommends Simpler HPV Vaccine Series for Young Adolescents
The CDC has changed its recommendation for the human papillomavirus vaccine administration from a routine three-dose series to a two-dose series for 9- to 14-year-old children.
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High-flow Nasal Cannula vs. Noninvasive Ventilation in Postextubation Failure: Does It Matter?
In this multicenter, randomized, clinical trial of critically ill adults at high risk for reintubation, high-flow conditioned oxygen therapy was not inferior to noninvasive mechanical ventilation with regard to preventing reintubation and postextubation respiratory failure within 72 hours of extubation.
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Should We Use Non-invasive Ventilation to Treat Acute Respiratory Distress Syndrome?
Managing acute respiratory distress syndrome (ARDS) with non-invasive ventilation was associated with increased failure as the severity of ARDS increased.
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Rehabilitation in the ICU: More Questions Than Answers
In patients with acute respiratory failure, standardized rehabilitation therapy consisting of passive range of motion, physical therapy, and progressive resistance exercise did not decrease hospital length of stay compared to usual care.