Internal Medicine
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High-sensitivity Cardiac Troponin
In a recent trial, the use of high-sensitivity troponin T did not increase the use of coronary angiography or stress testing, but did reduce ED length of stay and costs.
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Hemoconcentration Associated with Lower Mortality in Acute Heart Failure
Among patients hospitalized for acute heart failure, hemoconcentration was associated with reduced 90-day mortality and may be a useful marker for guiding therapy.
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Mechanical Circulatory Support in Cardiogenic Shock: Can Any Device Move the Mortality Needle?
In a small randomized trial of patients with cardiogenic shock secondary to acute myocardial infarction, the Impella heart pump failed to improve mortality compared with intra-aortic balloon counterpulsation.
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ECG Screening of Athletes
T-wave inversion confined to ECG leads V1-V2 is a normal variant, but T-wave inversion beyond V2 is rare and may warrant further investigation.
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Weight Loss to Make You Feel Better, Live Longer, and Lower Your Risk of Atrial Fibrillation
Significant and sustained weight loss through bariatric surgery reduced the risk of developing new-onset atrial fibrillation in a Swedish cohort of obese individuals.
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Hyperoxia in ICU Patients May Cause Harm
Patients randomized to maintain oxygen saturation between 94-98% experienced better outcomes than patients allowed to receive partial pressure of oxygen > 150 mmHg.
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Surviving Critical Illness: Who Returns to Work?
Three months after surviving critical illness due to respiratory failure or shock, more than 60% of survivors experienced a decrease in employment. At 12 months, almost half of survivors still experienced a decrease in employment.
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ECMO as a Rescue Strategy for Severe ARDS and Beyond
Extracorporeal membrane oxygenation has been used as a rescue therapy for patients with severe acute respiratory distress syndrome who fail to respond to traditional low tidal volume lung protective ventilation with optimal positive end-expiratory pressure interventions and other strategies.
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Clinical Briefs
In this section: treating genital herpes, atrial fibrillation remains a deadly problem, and extra precautions for diabetes patients.
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Plecanatide Tablets (Trulance)
Plecanatide is indicated for the treatment of chronic idiopathic constipation.