Internal Medicine
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California and Coccidioidomycosis: Be Careful About the Air You Breathe
Cases of coccidioidomycosis significantly increased in 2016.
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Polyneuropathy and Nutrition
Other than the identification of a specific vitamin or essential element deficiency, overall nutritional status does not appear to play any role in the development of idiopathic neuropathies in adults.
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Delafloxacin (Baxdela®)
Delafloxacin is a new broad-spectrum fluoroquinolone that was approved by the U.S. Food and Drug Administration in June 2017 for acute bacterial skin and skin structure infections.
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Lamotrigine for Myotonia
SYNOPSIS: In a randomized, double-blind, placebo-controlled treatment trial of patients with non-dystrophic myotonia, those treated with lamotrigine experienced significant improvement.
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REM Sleep, Not Slow-wave Sleep, Decreases Dementia Risk
In a series of clinical studies of cognitively normal people older than 60 years of age, disruption of REM sleep and reduced quantity of REM sleep increased the risk of developing Alzheimer-type dementia.
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Tau as a Biomarker of Acute and Chronic Traumatic Brain Injury
The ongoing search for reliable biomarkers of traumatic brain injury repeatedly has demonstrated the reliability of using plasma phosphor-tau levels to help distinguish injury from normal, and severe injury from mild injury.
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Fungal Endophthalmitis: Another Risk Associated With Intravenous Drug Use
A retrospective cohort study found that endogenous fungal endophthalmitis is associated with intravenous drug use and frequently results in poor visual outcomes despite appropriate surgical and antifungal therapy.
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Taste, Smell, and the Insular Cortex
Olfaction and taste appear to be localized in the insular cortex with bilateral representation.
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Rheumatic Heart Disease — The Global Situation
With advances in access to good medical care, the global burden of rheumatic heart disease is declining. However, there still is significant disease in resource-limited regions of the world.
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Chagas Seroprevalence in Military Personnel in Texas
A cross-sectional study of military trainees and instructors who spend significant time in field conditions was performed at Joint Base San Antonio to determine the prevalence of Trypanosoma cruzi infection. None tested positive by polymerase chain reaction nor by enzyme-linked immunosorbent assay or indirect immunofluorescent antibody.