Internal Medicine
RSSArticles
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Meropenem and Vaborbactam Injection (Vabomere)
The FDA has approved a new combination antibacterial for the treatment of complicated urinary tract infections.
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Is a Dabigatran Reversal Agent Effective?
A pragmatic clinical study of idarucizumab for counteracting the effects of the oral anticoagulant dabigatran showed rapid and complete reversal of its effects in patients with major bleeding or urgent surgery, without any adverse safety concerns.
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Mother Was Right: You Are What You Eat
In a study of simplified enterotypes as prognostic markers for successful body fat loss on two different diets, participants with a greater ratio of Prevotella to Bacteroides appeared more susceptible to lose body fat on diets high in fiber and whole grains.
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Diet High in Carbohydrates, Not Fats, Drives Mortality
A prospective epidemiological cohort study of people 35-70 years of age in 18 countries showed that a higher intake of carbohydrates increased total mortality, while the intake of fats of all kinds did not. A higher intake of saturated fat reduced stroke mortality.
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Aberrant Conduction or Ventricular Bigeminy?
How would you interpret the tracing? Are these multifocal (multiform) premature ventricular contractions?
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Clinical Briefs
In this section: managing diabetes; elective surgery; and nephrolithiasis patients.
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Tisagenlecleucel Suspension (Kymriah)
Kymriah is indicated for the treatment of patients up to 25 years of age with B-cell precursor acute lymphoblastic leukemia that is refractory or in second or later relapse.
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What Is the Ideal Target for Blood Pressure Control?
Researchers organized a study to address quality-of-life outcomes based on recent blood pressure recommendations.
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Do Antibiotics Reduce Hormonal Contraceptive Effectiveness?
Researchers conducted a systematic review of studies that evaluated the effect of concomitant non-rifamycin antibiotic use on hormonal contraceptive effectiveness. Although data are limited, there was no evidence to support the existence of drug interactions.
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Screening for Prostate Cancer May Offer Survival Benefits
Using a mathematical model to account for differences in implementation and baseline screening, researchers reassessed mortality data from two major studies and discovered that screening led to a 25-30% reduction of prostate cancer death in both.