Internal Medicine
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Can a Blood-Based Test Serve as a Biomarker for Parkinson’s Disease?
The authors of this proof-of-concept study proposed that a noninvasive assay detecting pathology-associated α-synuclein extracted from blood may reveal a reliable biomarker for Parkinson’s disease.
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Cutting Total Calorie Intake Is More Effective for Weight Loss
Researchers found monitoring total caloric intake may be more effective for losing weight than intermittent fasting.
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Bexagliflozin Tablets (Brenzavvy)
Bexagliflozin can be prescribed as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
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Do Spinal Cord Stimulators Really Help for Chronic Pain?
The results of a comprehensive analysis of a large clinical database regarding treatment of patients with chronic low back pain did not support the benefit of spinal cord stimulators compared to conventional medical management for chronic pain.
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Magnetic Brain Stimulation for Alzheimer’s Disease
Transcranial magnetic stimulation, targeted at the precuneus to help maintain a normal default mode network, shows some promise in slowing cognitive decline and maintaining normal electrophysiology in patients with mild to moderate Alzheimer’s disease.
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Ablation vs. Drug Therapy for Atrial Fibrillation, Revisited
A three-year follow-up of EARLY-AF, a study of relatively young and healthy patients with recent atrial fibrillation, showed cryoablation remains superior to drug therapy for preventing the development of persistent atrial fibrillation.
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An Easy Measure of Potentially Harmful Salt Intake
Those who rarely or never added salt to their food and strongly adhered to the Dietary Approaches to Stop Hypertension diet exhibited the lowest incidence of subsequent cardiovascular disease.
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Long-Term Air Pollution Exposure Could Raise Risk for Depression, Anxiety
Two research groups reported on breathing dirty air and how that affects mental health.
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A Patient with Pneumonia
The ECG in the figure was obtained from an elderly man who was admitted to the hospital with pneumonia. This ECG was obtained after his admission when he began to complain of chest pain. There are two important findings on this patient’s ECG. Can you identify them?
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Lecanemab-irmb Injection (Leqembi)
Lecanemab can be prescribed to treat Alzheimer's disease. Initiate this treatment in patients with mild cognitive impairment or mild dementia stage of disease, with confirmation of amyloid beta pathology.