Internal Medicine
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Bone Density as a Dementia Risk Indicator
Researchers found some associations between bone density loss and a higher risk of developing dementia.
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Sparsentan Tablets (Filspari)
Sparsentan can be prescribed to alleviate proteinuria in adults with primary immunoglobulin A nephropathy who are at risk of rapid disease progression — generally, a urine protein-to-creatinine ratio 1.5 mg/g or higher.
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Long-Term Maintenance Therapy After Percutaneous Coronary Intervention
An extended six-year follow-up of the HOST-EXAM study revealed the consistent benefit of the primary endpoint of fewer major cardiovascular events and less bleeding with clopidogrel vs. low-dose aspirin monotherapy in post-percutaneous coronary intervention patients who were on dual antiplatelet therapy for one year.
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Does COVID Vaccination Prevent Car Crashes?
In a large study, lack of COVID vaccination was associated with more incidents of car crash injuries.
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Self-Treatment of Recurrent Benign Paroxysmal Positional Vertigo
Using a cell phone-based app, self-treatment of recurrent benign positional paroxysmal vertigo was feasible and effective in most patients.
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Healthy Lifestyle Behaviors Linked to Slower Memory Decline
In a population-based, prospective cohort study of 29,000 Chinese adults, researchers found healthy lifestyle was associated with slower memory decline, even in the presence of the apolipoprotein E4 allele.
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More Daily Steps Lowers Cardiovascular Disease Risk Among Older Adults
Researchers reported that for every additional 500 steps per day, the risk for heart disease, heart failure, and stroke declined by 14% among adults age 70 years and older.
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Asymptomatic with Inverted T Waves
The ECG in the figure is from a healthy young adult without symptoms. Clinicians recorded this tracing as part of the patient’s employment physical exam. Is the T wave inversion likely to be a normal variant?
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Daprodustat (Jesduvroq)
Daprodustat can be prescribed to treat anemia caused by chronic kidney disease in adults who have been receiving dialysis for at least four months.
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Does Surviving an ECMO Stay Put Patients at Greater Risk for Mental Health Problems?
Survivors of extracorporeal membrane oxygenation (ECMO) demonstrated a modest increase in risk of new mental health diagnoses after discharge vs. ICU survivors who do not undergo ECMO.