Internal Medicine
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Plant-pharmaceutical Interactions in the Scientific Literature
Case reports and observational studies revealed that certain medical conditions and a select few botanical medicines have adverse plant-pharmaceutical interactions.
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B Vitamins and Lung Cancer Risk
These researchers investigated the use of supplemental vitamin B6, folate, and B12 and the risk of lung cancer in 77,118 participants in the Vitamins and Lifestyle cohort, finding an increased risk of lung cancer in men, which was exacerbated by smoking.
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A Review of Heart Failure and Current Therapeutic Strategies
The management of heart failure falls primarily on the primary care physician. Because of the Medicare financial penalty on hospitals for readmissions, primary care physicians need to be cognizant of the updated treatment options and work with colleagues across multiple disciplines to prevent unnecessary hospitalizations and improve outcomes.
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Salivary microRNA as Biomarker to Predict Prolonged Concussion Symptoms
In a prospective cohort study of pediatric patients, aged 7 to 21 years, diagnosed with concussion, salivary microRNAs were found to be a potential biomarker for predicting prolonged concussion symptoms.
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Treatment for Autoimmune Small-fiber Neuropathy
The cause of most cases of small-fiber neuropathy is uncertain, but many patients have accompanying autoimmune biomarkers. In a carefully selected group of such patients, intravenous immunoglobulin treatment appears to provide benefit.
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Proceedings From the International Stroke Conference, Los Angeles, February 2018
Message from the editor: The following reviews of studies presented at the 2018 International Stroke Conference were written after my personal attendance at the presentations, followed by review of the simultaneous publications in the journals Stroke, The New England Journal of Medicine, JAMA Neurology, and the Journal of the American Medical Association.
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Infectious Disease Alert Updates
Food Tray Contamination With MRSA/VRE; Hospital Ice Machines Contaminated With Bacteria; Significance of Toxocara Serologies?
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What Do the Urinary Microbiota and Incontinence Have to Do With Each Other?
Increased diversity of the microbiota in women is associated with urgency urinary incontinence symptoms but not with stress urinary incontinence symptoms.
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Does Adding Rifampin to Standard Therapy Improve Outcomes in Patients With Staphylococcus aureus Bacteremia?
The addition of rifampin to standard therapy failed to provide significant benefit to patients with bacteremia due to Staphylococcus aureus.
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New Agent for Treatment of Chagas Disease Disappoints in Clinical Trial
A randomized, controlled trial of E1224 (a ravuconazole prodrug) in different doses and durations was studied in adult patients with chronic indeterminate Chagas disease. Parasite clearance was observed in treated patients, but the response was transient in most patients.