Internal Medicine
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Prediction of Persistent Post-concussion Symptoms After Mild Traumatic Brain Injury
Persistent post-concussion syndrome may last for more than six months, and risk factors include female sex, neck pain, headache, and post-concussive symptoms at two weeks after the injury.
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Is It Acceptable to Die of Aortic Stenosis Without a TAVR?
Investigators performed a retrospective analysis of 544 patients undergoing transcatheter aortic valve replacement (TAVR) at one center to assess the contribution of a frailty score to the Society of Thoracic Surgeons (STS) risk score for predicting mortality post-procedure. The frailty score was found to be an independent predictor of 30-day and one-year mortality and additive to the STS score.
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Prognostic Value of Left Ventricular Strain in Chronic Aortic Regurgitation
A retrospective observational study of the incremental value of echocardiographic global longitudinal strain (GLS) for predicting mortality in asymptomatic patients with moderate to severe aortic regurgitation and normal left ventricular function showed that GLS was a predictor of mortality. However, GLS was not as robust as undergoing surgery was for predicting mortality.
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Vegetarian Diet vs. Mediterranean Diet to Reduce Cardiovascular Risk
A randomized, open, cross-over study of a vegetarian diet (VD) compared to the Mediterranean diet (MD) over three months showed that both reduced body weight and body fat mass. The VD decreased LDL cholesterol, and MD reduced triglyceride levels. The MD reduced inflammatory markers, and the VD reduced vitamin B12 levels.
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Is the Type of Myocardial Infarction Important?
An observational study of hospitalized patients with type 1 or 2 myocardial infarction (MI) or myocardial injury showed that mortality is higher in type 2 MI or myocardial injury patients compared to type 1 MI patients.
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Creatinine Bumps and Renal Tubular Injury in Acute Heart Failure
In patients with acute heart failure who receive aggressive diuresis, worsening renal function identified by a rise in serum creatinine or cystatin C is not indicative of kidney tubular injury.
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Infectious Disease Alert Updates
House Mice as Vectors; Eat Your Fruits and Vegetables — or You Might Get TB!
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Another Reason to Get the Flu Shot Every Year
In a case-control study, among older adults, repeated vaccination for influenza was twice as effective in preventing severe influenza compared to non-severe influenza in patients who were admitted to the hospital.
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Fosfomycin or Nitrofurantoin for Cystitis?
A single dose of fosfomycin was found to be less effective than five days of thrice-daily dosing of nitrofurantoin in the treatment of symptomatic lower urinary tract infection in women.
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PANDAS: Examining the Evidence for Treatment Options
Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS) is a proposed disorder first named in 1998 that has been the subject of controversy in the literature. Although the debate has waned somewhat in the United States, it remains a topic of discussion in many European medical journals. A recent systematic review found no evidence for antimicrobial or immunomodulatory treatment for this condition.