Internal Medicine
RSSArticles
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The Pulmonary Embolism Rule-out Criteria in Low-risk Patients
A cluster randomized trial of the pulmonary embolism rule-out criteria (PERC) compared to usual care for patients estimated to be at low risk of pulmonary embolus (PE) in EDs showed that PERC was non-inferior to usual care at identifying patients who would be free of symptomatic PE at three months, resulting in less use of healthcare resources.
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Saffron as Adjunctive Therapy for Opioid Withdrawal
A small, poorly designed study hints at some adjunctive treatment benefit for saffron powder in people weaning off narcotic medications.
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Mindfulness-based Intervention in Patients With Generalized Anxiety Disorder
Reductions in stress markers for patients with generalized anxiety disorder were found using mindfulness-based stress reduction intervention.
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Tai Chi or Aerobics: Which Is Better for Fibromyalgia?
In this randomized, controlled trial, researchers found that tai chi shows equal or greater effect than aerobic exercise for addressing symptoms of fibromyalgia, and that more effect is obtained with longer duration of tai chi practice.
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Dairy Intake and Risk of Parkinson’s Disease
Frequent consumption of dairy products is associated with a modest increased risk of Parkinson’s disease (PD) in women and men. In addition, intake of high-fat dairy is associated with decreased risk of PD.
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Diabetic Retinopathy, Associated Comorbidities, and Treatment Considerations
Diabetic retinopathy is a complex disorder of the microvascular and neuronal structure of the retina. Although poorly understood, the problem does not start in the retina, but rather begins through systemic metabolic dysfunction, which causes damage to retina vessels. This article will review the structure of the retina, the systemic pathophysiology of diabetes, the resulting damage to retinal structure and function, comorbidities, traditional treatments, and prevention and treatment for diabetic retinopathy and its comorbidities.
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Anti-MAG Antibodies: Clinical and Therapeutic Aspects
Anti-MAG antibody-associated neuropathy may present as many disorders, including small fiber neuropathy, sensorimotor neuropathy, Guillain-Barré-like syndrome, and multifocal motor neuropathy. Rituximab appears to be the best therapeutic option.
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Longitudinal tau PET as an Outcome Measure for Clinical Trials
tau PET imaging shows progression of brain Alzheimer’s pathology over time and correlates with cognitive impairment better than amyloid PET. In future clinical trials, tau PET can serve as a biomarker for Alzheimer’s disease progression.
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What Are the Early Predictors for Post-traumatic Epilepsy After Injury?
Following traumatic brain injury, early (first five days after injury) epileptiform abnormalities on EEG were seen more commonly in patients with subsequent post-traumatic epilepsy (PTE), compared to controls, and were found to be a significant and independent predictor of PTE. The presence of subdural hemorrhage was the only other independent predictor of PTE.
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Intracranial Pressure Changes in Mild Traumatic Brain Injury
After an exhaustive review of the animal and human studies literature regarding mild traumatic brain injury (mTBI), Haider et al. did not reach consistent conclusions regarding evidence for intracranial pressure elevation in human patients who sustain an mTBI.