Internal Medicine
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Should Aspirin Be Used for Primary Prevention of Cardiovascular Events?
The conclusion from a series of groundbreaking studies is that primary prevention of cardiovascular disease and death by using daily low-dose aspirin is not recommended and should be reserved for those instances in which secondary prevention has been demonstrated to be effective in randomized, clinical trials.
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Costs and Consequences of Chronic Pain Among U.S. Adults
Annually, chronic pain accounts for an estimated $560 billion in direct medical costs, lost productivity, and disability programs. Identifying populations at risk is the first step for developing targeted interventions for pain management.
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Risk of Infective Endocarditis Revisited
In a comparison of patients with infective endocarditis (IE) and either bicuspid aortic valve (BAV) or mitral valve prolapse (MVP) vs. other IE patients at high or low-to-moderate risk of IE, BAV and MVP patients were more likely to exhibit viridans group streptococci infections of suspected odontogenic origin and cardiac complications at similar rates to high-risk patients.
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Effect of Diet on Hippocampal Volume in a Population at Risk for Alzheimer’s Disease
MRI of the brain in community-dwelling people (average age, 60 years) revealed that a long-term, high-quality diet was associated with larger hippocampal volumes after an average interval of 11 years.
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Acupuncture as Adjunct Therapy for Infertility in Polycystic Ovary Syndrome
Acupuncture as an adjunctive therapy for treating infertility in Chinese women with polycystic ovary syndrome receiving clomiphene citrate or placebo offered no benefit over sham acupuncture.
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Acupuncture for Pain Control in the Emergency Department
In this study, researchers treated pain in the emergency department with acupuncture alone, acupuncture with conventional medication, or medication alone. They found acute efficacy was similar, although not optimal, for all modalities.
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Chocolate for Primary Prevention of Atrial Fibrillation
In a large, population-based, prospective cohort study of Danish people aged 50-64 years, researchers found that chocolate intake was inversely related to incidental rates of atrial fibrillation and atrial flutter.
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Homeopathic Remedies and Dietary Supplements in 2018: Weighing Benefits and Risks
More than half of Americans are using supplements or over-the-counter medications. Practitioners need to understand how their patients are using supplements and be able to provide accurate, factual advice on dietary supplements and homeopathic preparations. This article will evaluate each category for benefits and risks and provide details on how to research each product for available information. In addition, the article will assess various recommendations, including examples in weight loss, energy enhancement, and performance products.
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Oral Anticoagulant-associated ICH
Intracerebral hemorrhage is the most dangerous and feared complication of oral anticoagulation and leads to a high mortality. Debate continues about the relative risk of hemorrhage with two classes of oral anticoagulants.
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A Biomarker to Help With Neurologic Prognosis After Cardiac Arrest
Determining the prognosis of neurological outcome after cardiac arrest is notoriously difficult. Neurofilament light chain is a new potential biomarker, for which elevated levels in the spinal fluid or blood indicate axonal injury in several neurological diseases.