Internal Medicine
RSSArticles
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The Right Ventricle During Heart Failure With Preserved Left Ventricular Ejection Fraction
A retrospective longitudinal study of heart failure with reduced left ventricular ejection fraction shows that right ventricular function deteriorates more rapidly than left ventricular function and is associated with increased mortality.
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New Insights Into Young Acute Myocardial Infarction Patients
A retrospective contemporary review of STEMI patients younger than 35 years of age shows that these patients are predominantly overweight men who smoke (some abuse drugs and present with dyslipidemia).
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Transcatheter Mitral Valve Replacement
A large registry study of transcatheter mitral valve replacement showed excellent results in failed bioprostheses but less overall success in failed mitral valve repairs with rings and conditions associated with mitral annular calcium.
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Early Cardiac Catheterization After Resuscitation From Cardiac Arrest
In this first-ever randomized trial about comatose patients without ST-segment elevation who have been resuscitated from cardiac arrest, immediate coronary angiography showed no benefit over delayed coronary angiography in terms of 90-day survival.
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Team-Based Approach Associated With Better Outcomes in Cardiogenic Shock
Implementation of a standardized, team-based approach to cardiogenic shock resulted in improved 30-day survival compared to historical controls.
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Saline vs. Balanced Crystalloids in Critically Ill Adults
Balanced crystalloids appear to reduce in-hospital mortality in critically ill patients with sepsis or without traumatic brain injury and may reduce in-hospital mortality in the entire cohort of critically ill patients.
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Presepsis Pathways: Can We Predict Mortality After Sepsis Hospitalization?
Using a latent profile analysis in observational cohort studies of patients hospitalized for sepsis, investigators identified subtypes of patients based on inpatient healthcare facility use in the year prior to sepsis hospitalization and correlated to 90-day mortality.
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Ventilator-Associated Pneumonia and Hospital-Acquired Pneumonia: Prevention and Treatment
Ventilator-assisted pneumonia and hospital-acquired pneumonia pose significant risks to hospitalized patients and increase the cost of care. It is essential to institute measures to reduce the risk of these pneumonias and to recognize and treat them early when they occur. Treatment is a balance of ensuring adequate antimicrobial coverage in those who already are seriously ill while not unduly exposing them to the risks of medication side effects and higher rates of resistant organisms that come with the use of broad-spectrum antibiotics.
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Brexanolone Injection (Zulresso)
Brexanolone is indicated for the treatment of postpartum depression.
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Update on Treatments for Vulvovaginal Atrophy
As with many clinical conditions, the spectrum of genitourinary syndrome of menopause requires the clinician to consider the effect on the patient’s quality of life. Although situational lubricants and regular moisturizers effectively pacify many symptoms, local estrogen is a safe, effective, and affordable way to treat the vulvovaginal changes of menopause.