Internal Medicine
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Can Physical Activity Thwart the Negative Cardiometabolic Effects of Obesity?
Compared to normal-weight workers, overweight or obese employees in Spain exhibited a higher prevalence of risk factors for cardiovascular disease, which can be partially mitigated by regular exercise.
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Walk! A Long-Term Observational Investigation of Knee Osteoarthritis
The results of an observational study of more than 1,000 individuals age 50 years and older with knee arthritis revealed regular walking for exercise correlated with fewer reports of new knee pain and slower disease progression, as verified by radiographic evidence at eight-year follow-up.
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Antidepressants for Chronic Pain: Do They Work?
Antidepressant medications have been widely used for treating a variety of chronic pain disorders, but strong evidence to support their efficacy is lacking. Some patients may respond, but available data do not help us determine which agents may be helpful in a specific type of chronic pain condition.
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Alcohol: Double-Edged Sword, or Hatchet?
Researchers reported consuming two to 14 alcoholic drinks per week was associated with fewer major adverse cardiovascular events, which the authors noted could be explained in part by less stress-related neural activity demonstrated on PET and CT scans.
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Physician Group Says to Start Colon Cancer Screening at Age 50 Years
Patient advocates push back, standing by other recommendations that set the age at 45 years.
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Cardiologists Consolidate, Update Guidance for Chronic Coronary Disease Management
Researchers incorporated shared decision-making, social determinants of health, and team-based care principles.
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What Kind of Bundle Branch Block?
Assuming QRS widening in a supraventricular rhythm is not the result of hyperkalemia or other toxicity, and assuming the patient has not been diagnosed with Wolff-Parkinson-White syndrome, classification of 12-lead ECG conduction disturbances can be simplified into one of three basic categories. The tracing in the figure illustrates this concept.
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Donislecel-jujn Allogenic Pancreatic Islet Cellular Suspension (Lantidra)
Lantidra can be prescribed to adults with type 1 diabetes who cannot approach target HbA1c levels because of current repeated episodes of severe hyperglycemia despite intensive diabetes management and education.
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Report from the 2023 American Diabetes Association Scientific Sessions
At the 2023 American Diabetes Association Scientific Sessions, experts presented key updates, advances, and best practices for patient care. A selection of presentations relevant to the internal medicine and primary care community is presented here.
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Colchicine Tablets (Lodoco)
The FDA has approved the first anti-inflammatory drug to lower the risk of cardiovascular events occurring in adults with established atherosclerotic disease or with multiple risk factors.