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VCT substantially improves imaging of vascularization in tumors and offers a promising tool for preclinical studies of tumor angiogenesis and antiangiogenic therapies.
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Peripheral neuropathy in NF-1 patients is a marker for poorer prognosis and mandates heightened vigilance for malignancy and spinal cord complications.
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Merck announced on September 30th that it is voluntarily withdrawing rofecoxib (Vioxx) from the worldwide market.
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O'Mathuna DP. Creatine to improve muscle strength. Altern Med Alert 2004;7(11):128-131.
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Greenfield RH. Acunpuncture for PONV. Altern Med Alert 2004;7(11):131-132.
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A retrospective study of 24,112 patients with coronary heart disease showed increased 30-day mortality in patients who received one or more blood transfusions for anemia compared to comparable patients not transfused.
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B-type natriuretic peptide (BNP) is a biomarker released by cardiac ventricular myocytes. Its usefulness is mainly in the emergency room for the evaluation of acute dyspnea, to evaluate for cardiac failure. BNP may have usefulness as a screening test for preclinical heart disease, for risk stratification and for guidance with therapy.
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Although regular aspirin use reduces the risk for colorectal adenoma formation as shown in previous randomized-controlled trials, the protective effect now seems to be greatest at substantially higher doses (> 14 standard tablets/week) than currently recommended for cardiovascular prophylaxis.
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The FDA has approved a combination product of amlodipine and atrovastatin for the treatment of patients with comorbid hypertension and hypercholesterolemia.