Internal Medicine
RSSArticles
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CRP and Reduction of Antibiotic Use in Acute Exacerbations of COPD
Point-of-care C-reactive protein testing can safely and effectively reduce antibiotic use in patients with acute exacerbations of COPD.
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Treating Infective Endocarditis in Moderate-Risk Patients
There are patients with a moderate risk of infective endocarditis who may warrant consideration of antibiotic prophylaxis.
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Calcitonin Gene-Related Peptide Targeting Therapies for Migraine
Two randomized clinical trials showed that calcitonin gene-related peptide targeting therapies are effective and safe for primary headache disorders.
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Size Matters Regarding Left Heart Valve Vegetations
An international registry study of left-sided valvular infective endocarditis patients revealed that large vegetations (> 10 mm) are associated with increased mortality at six months, but not if early surgery is performed.
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Blood Pressure Targets in the Elderly
The authors of a large population study found that reducing blood pressure to < 140/90 mmHg is associated with increased mortality, and mortality was highest in those with previous cardiovascular events and age > 80 years.
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Is There a Role for Surgery in Isolated Severe Tricuspid Regurgitation?
A retrospective single-center analysis of patients with isolated severe tricuspid regurgitation revealed no survival benefit from tricuspid surgery.
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Is It Safe to Stop Digoxin for Heart Failure?
In a large older patient heart failure with reduced ejection fraction hospitalizations database, the outcome of withdrawing digoxin vs. continuing digoxin was examined at 30 days and up to four years of follow-up. Withdrawing preadmission digoxin in hospital resulted in higher mortality at 30 days and more readmissions at six months, one year, and four years.
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Complete Revascularization After STEMI: Do We Finally Know the Answer?
In this largest trial to date, patients who were randomized to complete revascularization by percutaneous coronary intervention (PCI) following successful intervention at the time of ST-elevation myocardial infarction (STEMI) had a lower risk of cardiovascular death, myocardial infarction, and ischemia-driven revascularization vs. patients who underwent culprit lesion-only PCI.
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Are the Changes New, Recent, or Old?
Imagine examining the ECG in the figure below without any accompanying clinical information. How would one interpret this tracing? What might one suspect is going on?
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Imipenem, Cilastatin, and Relebactam Injection (Recarbrio)
The FDA has approved a new antibacterial drug combination for complicated urinary tract infections and complicated intra-abdominal infections.