Internal Medicine
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Blood Pressure Targets in the Elderly
The authors of a large population study found that reducing blood pressure to < 140/90 mmHg is associated with increased mortality, and mortality was highest in those with previous cardiovascular events and age > 80 years.
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Vaping and Severe Acute Pneumonitis
Hundreds of cases of lung injury possibly related to vaping have been reported to the CDC. Evidence to date suggests the illness is a form of acute lipoid pneumonia likely related to inhalation of lipid materials.
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What Might Account for the ST-T Changes?
The ECG in the figure was obtained from a 65-year-old woman who presented with an exacerbation of heart failure. A medical history revealed she was taking multiple medications. The patient was dyspneic and complained about intermittent chest pain.
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Pitolisant Tablets (Wakix)
Pitolisant should be prescribed to treat excessive daytime sleepiness in adult patients with narcolepsy.
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When Did You Last Take an Antibiotic?
Approximately half of U.S. residents with health insurance filled an antibiotic prescription over a two-year period.
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Risk of Neuropathy With Fluoroquinolones
As a class, fluoroquinolones are some of the most commonly used antibiotics worldwide. Their use carries a significant risk of neurotoxicity, for both the peripheral and central nervous system.
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Neuropathy After Total Knee Arthroplasty
In a large series of cases from the Mayo Clinic, 54 cases of new neuropathy occurred in 14,450 total knee arthroplasties. Most were isolated peroneal neuropathies. No specific risk factors were identified.
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NOACs vs. Warfarin: What Are the Data in Patients With Traumatic Brain Injury and Intracranial Hemorrhage?
A three-year analysis of a prospectively maintained database with traumatic brain injury patients revealed that novel oral anticoagulant use is associated with increased risk of intracranial hemorrhage progression, neurosurgical intervention, and mortality.
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The Health Effects of Magnesium: Part 1
Magnesium, an important dietary ingredient and supplement, has both long-standing and emerging clinical evidence for efficacy in treating a variety of health conditions. To do this mineral justice, we are covering this extensive information in two parts. Part 1 will focus on basic science and physiology, general dietary recommendations, supplemental forms, laboratory testing, and dosing. Part 2 will review some of the clinical trials and research on the connection between low magnesium intake and diseases, such as diabetes, as well as the data on the use of supplemental magnesium for treatment of these diseases.
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Gingko Benefits for Tinnitus?
Twelve weeks of twice-daily Ginkgo biloba extract improved symptoms as effectively as pentoxifylline in 200 adults with chronic tinnitus.