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Of 583 children < 18 years of age tested for anti-neutrophil cytoplasmic antibody (ANCA) at Boston Children's Hospital from 1996 to 2006, 27 children had a history of minocycline administration, with clinical and laboratory findings of autoimmunity. Of these 27 children, 19 were female (70%).
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A retrospective study of all 5,817 neonates (¡Ü 28 days of age) admitted from the Emergency Department to Texas Children's Hospital from 2001 through 2005 found that 8.6% (95% CI, 7.9-9.3%) had documented viral infections (8.4% non-HSV and 0.2% HSV), and 4.6% (95% CI, 4.1-5.2%) had documented serious bacterial infections.
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Approximately 50% of b-cell function has been lost at the time of initial diagnosis of type 2 diabetes.
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Lubiprostone, the new drug for idiopathic constipation, improved PEG-based colonoscopy preparation.
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Previously undiagnosed cancer is frequent in patients with an unprovoked VTE and is more often detected with an extensive cancer screening strategy than with a limited screening strategy.
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A new agent has been approved by the fda for the treatment of thrombocytopenia associated with chronic immune thrombocytopenia purpura (ITP).
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Terminally ill cancer patients who had end-of life discussions with their physician had better quality of life during their last week and their caregivers had an easier bereavement.
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Ongoing safety review of tiotropium; raloxifene reduces the risk of endometrial cancer; one-day treatment with famciclovir may be as effective as 3-day treatment with valacyclovir; new Clinical Practice Guideline from the American College of Physicians regarding pharmacologic treatment for low bone density and osteoporosis; FDA Actions.
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