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Two recent studies have demonstrated the bene-ficial effects of nicotinic acid (niacin) on carotid artery atherosclerosis.
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Intensive lipid lowering with statin therapy (atorvastatin 80 mg) in patients presenting with acute coronary syndromes (ACS) resulted in improved outcomes compared to treatment with moderate lipid lowering (pravastatin 40 mg) in the PROVE-IT TIMI-22 study (Cannon et al. N Engl J Med.
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Anticoagulation during percutaneous coronary intervention (PCI), although necessary to prevent thrombus formation on the interventional equipment, can lead to significant morbidity from bleeding complications, particularly if the dosage is excessive.
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In this issue: Two oral medications for relapsing-remitting MS in phase III development; antihypertensives find new uses; Ginkgo biloba does not prevent cognitive decline in elderly; and FDA Actions.
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Although delirium is a common complication of critical illness associated with considerable morbidity and mortality and haloperidol is widely used for treatment of the problem, there are no controlled studies examining whether this or other medications are effective therapeutic modalities in ICU patients.
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Each year, about 795,000 strokes occur in the United States; 85% of these are acute ischemic strokes.
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The incidence, severity, and costs of clostridium difficile infection (CDI) are increasing, creating a substantial burden for patients and institutions. Guidelines for prevention of CDI are complex and not consistently followed.