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A 44-year old woman with a history of acute myelogenous leukemia (AML) who recently completed a third-cycle of consolidation chemotherapy with idarubicin and cytarabine presented with fever and abdominal pain.
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Bedaquiline (a unique diarylquinoline) was studied vs. placebo in a prospective randomized trial when added to a standard 5-drug regimen in the treatment of multidrug-resistant (MDR) tuberculosis. Treatment with bedaquiline when added to a preferred background for 24 weeks resulted in significantly more and faster culture conversion than placebo.
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Pharyngitis is a very common infection resulting in more than 6 million annual office visits by adults in the United States. The ability to distinguish pharyngitis caused by group A streptococci (GAS) from other etiologies (e.g. viruses) is important because untreated GAS can have serious consequences including peritonsillar abscess and rheumatic fever.
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The healthcare system in Liberia has had to go through a complete reboot after every single hospital in the city of Monrovia closed down to be decontaminated with bleach water as a result of Ebola cases landing in emergency rooms, outpatient clinics and medical wards
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A preliminary report from Missouri suggests that enterovirus 68 is responsible for a large outbreak of respiratory disease in children. Typically, there is a rapid onset of respiratory symptoms with wheezing, and intensive care is required for about 15% of affected patients.
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The American Geriatrics Society has published guidelines on the use of vitamin D supplementation for the prevention of falls in the elderly, but some researchers are not on board with this.
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Mitochondrial oxidative stress and damage is connected to neuronal cell death and behavioral outcomes after TBI. Antioxidant treatment with the amide form of N-acetylcsyteine, which has central nervous system (CNS) bioavailability, was shown to improve markers of damage and cognitive function in rats when provided by intraperitoneal injection post experimental TBI.
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This randomized, parallel group study over 12 months found greater weight and cardiovascular risk benefits in obese adults eating a low-carbohydrate diet vs a low-fat diet.
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A polysaccharide-rich extract of turmeric rhizome provided benefits in people with knee osteoarthritis.