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In 1998, Beyth and colleagues developed a modified outpatient bleeding risk index. In this prospective study conducted at the University of Ottawa, 222 patients with diagnosed pulmonary embolism or deep venous thrombosis were observed for an average of 18.5 months.
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Elevated homocysteine levels have been associated with atherosclerosis. Folic acid supplementation is a simple, inexpensive way to reduce homocysteine levels, which has become popular for secondary prevention in patients with coronary artery disease (CAD), despite a paucity of long-term clinical trial data. Thus, Liem and colleagues studied 593 patients with stable CAD on statins who were randomized to open-label folic acid 0.5 mg/d or standard care, which included aggressive pursuit of lipid goals.
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Nasally Administered Flu Vaccine Comes to United States; Paxil: Not
Recommended for Children; Prilosec Granted OTC Status; Finasteride and
Prostate Cancer; Xolair: First Biologic Agent for Asthma; West Nile
Virus Update; Study Shows COX-2 Inhibitors Appear Safe with Aspirin in
Asthma Patients; Lamictal Approved for Bipolar Disorder
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Increase in Blood Glucose Concentration During Antihypertensive
Treatment as a Predictor of Myocardial Infarction; Adverse Drug Events
in Ambulatory Care; Prevention of Hip Fracture by External Hip
Protectors; Rapid MRI vs Radiographs for Patients with Low Back Pain;
Effectiveness of Anticholinergic Drugs Compared with Placebo in the
Treatment of Overactive Bladder; A Randomized Trial of a Low
Carbohydrate Diet for Obesity
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Affecting virtually every aspect of our health care system, the stunning growth and rapid integration of hospital-based medicine has affected the practice of both medicine and surgery by significantly modifying the delivery of inpatient, outpatient, and subacute care. This article details the history of hospitalists in the United States by defining the practice of hospital medicine and reviewing the evidence extolling its virtues. Although hospital medicine appears here to stay, work must still be done to address a number of current and future issues facing hospitalists and the health care community embracing them.
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Difficulties in Diagnosing Intestinal TB; Can Human Betaretroviruses Trigger Autoimmune Disease?; Rifampin and Pyrazinamide No Longer Recommended for Latent TB; Meningitis in Children with Cochlear Implants
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Randomized trial data suggest that linezolid is superior to vancomycin in the treatment of nosocomial MRSA pneumonia.
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Experiments suggest that bacteria may persist within bladder epithelial cells in a biofilm contained within pods, thus accounting for bacterial persistence manifested as chronic or recurrent urinary tract infection.
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Another study has shown an increase in mortality associated with the use of an oral IIb/IIIa receptor antagonist.
