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Almost all patients with diabetes eventually develop neuropathy. New therapeutic options for the control of painful diabetic neuropathy are constantly being investigated.
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Mutations in a-synuclein and parkin have been described in families with Parkinsons disease, and both gene products are involved in the function of the proteosome, a major pathway for degradation of proteins within the cell.
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HMG-CoA reductase inhibitors (statins) are known to reduce the risk of myocardial infarction and stroke. Statins are effective not only as cholesterol lowering agents but also have beneficial effects on endothelial cell function, as well as antithrombotic and anti-inflammatory effects.
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Vigabatrin (VGB) is an antiepileptic drug (AED) whose putative mechanism of action is to increase inhibitory tone in the brain by blocking the metabolism of gamma-amino butyric acid (GABA) by irreversibly binding to GABA transaminase.
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Benign hyperckemia may be defined as serum elevation of creatine kinase (CK) in an asymptomatic patient or in a patient with nonspecific symptoms, including muscle pain, fatigue, cramps, stiffness, normal neurological examination, and normal or nondiagnostic electrodiagnostic (nerve conduction studies and electromyography) studies.
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Taylor and associates report a case of Hashimoto encephalopathy in an adolescent girl with a 9-month history of what was initially diagnosed as chronic fatigue syndrome.
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Cardiac resynchronization reduces the mortality of progressive heart failure in patients with symptomatic left ventricular dysfunction and dyssynchrony.
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In this study, a European consortium of investigators evaluated the ability of an automatic external cardioverter defibrillator (AECD) to detect and treat arrhythmias in the in-hospital setting.
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In guidance that should spell millions of dollars saved for the nations hospitals, the Centers for Disease Control and Prevention (CDC) is calling a halt to routine changes of ventilator breathing circuits.