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This report is a detailed analysis of the approximate 6000 diabetics in the Heart Protection Study, which investigated the efficacy of simvastatin (simva) and antioxidant vitamins.
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Sweeney and colleagues from the Mode Selection Trial report on the effects of ventricular pacing in patients with sinus node dysfunction.
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Sutton and colleagues from New Zealand explored the concept that natriuretic peptide levels (ANP, BNP) may aide in the determination of the severity of mitral regurgitation.
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Current supportive heart failure therapy has reduced morbidity and mortality, but adverse outcomes are still frequent. Clearly, an approach based upon eliminating the cause of myocardial dysfunction would be advantageous. This study is an attempt to pursue this line of therapy for viral myocarditis using the antiviral agent INFB.
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This study, following on the heels of the recent negative trial in postpercutaneous coronary stenting patients, suggests that we have more to learn about the role of folic acid and homocysteine in CAD.
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Rea and colleagues report a longitudinal survey of cardiac arrests in King County, Wash, (excluding the city of Seattle) from 1977 to 2001. The study, from a region with perhaps the best emergency medical system in the country, adds important data.
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This study shows that intravenous amantadine is beneficial in reducing the pain of painful peripheral neuropathy, with an effect sustained for at least 1 week after an infusion.
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Only tamoxifen has enough evidence to be recommend for the prevention of breast cancer, and its use is limited to very high-risk women with a low risk of side effects.
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Recent NSAID use is a risk factor for acute diarrhea, a consideration for general physicians along with GI specialists.