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Wernicke-Korsakoff syndrome, consisting of the triad of mental status changes, ocular motility abnormalities, and ataxia, in the setting of thiamine deficiency, remains a clinical diagnosis.
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Hyperkalemic periodic paralysis has now been well characterized clinically, physiologically, and genetically.
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An outbreak of fungal meningitis and paraspinal infections occurred over the past year due to contaminated methylprednisolone injections.
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Subjects with Lesch-Nyhan disease and Lesch-Nyhan variant have significant reductions in brain size in the basal ganglia as well as several cortical areas.
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Most children presenting for care related to fever at two Tanzanian outpatient clinics had acute respiratory infections. Malaria accounted for "only" 11% of diagnoses and typhoid fever for 4%.
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Posaconazole oral suspension (Noxafil® oral suspension, Merck) has been, for several years, indicated for treatment of orophayngeal candidiasis as well as for prophylaxis of invasive Aspergillus and Candida infections in patients at risk. Posaconazole delayed-release tablets (Noxafil® delayed-release tablets, Merck) were recently FDA-approved for prophylaxis of invasive Aspergillus and Candida infections in immunocompromised patients 13 years of age and older.
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A national survey of parents found that information from the CDC about vaccines and adverse facts may not be effective in correcting parental misperceptions. Some attempts to heighten parental awareness about vaccine-preventable diseases and vaccine safety may actually be counterproductive.
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Not a week goes by where I do not see at least one or two newly diagnosed cases of syphilis and not just in my HIV+ MSM patients. Syphilis is beginning to appear in young heterosexuals as well.
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Autologous CD4+ T-cells modified to delete CCR5 by Zinc-finger nuclease (ZFN) were infused into 12 HIV-infected patients. Cells survived in the circulation of patients and provided some control of viral replication and immune reconstitution after interruption of antiretroviral therapy.