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Curcumin, the primary active constituent of curcuma longa, is well known for its antioxidative and anti-inflammatory actions, but also has been used traditionally for conditions including depression and anxiety in Chinese and Ayurvedic medicine
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In a survey of consecutive myeloma patients from the Mayo Clinic on hypothetical constructs with varying expectations regarding overall survival benefit, toxicity, and financial burden, it was found that the majority of patients would not choose maintenance if toxicity was more than just mild and overall survival benefit was less than 1 year. Increasing financial burden (drug cost) also reduced the numbers that would choose maintenance therapy. Males were more likely than females to choose treatment in each of the scenarios presented.
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Inhaled apomorphine, at doses up to 0.8 mg, appears safe and well tolerated by patients with Parkinsons disease, but does not result in significant improvement in wearing off periods, at the tested doses.
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Administrative databases may not give an accurate representation of hospital-acquired pressure ulcer rates and may be inappropriate for use to compare hospitals and determine financial penalties.
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A fixed dose of oral apixaban alone was noninferior to conventional therapy for the treatment of acute venous thromboembolism and was associated with significantly less bleeding.
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This long-term epidemiological study shows an association between glaucoma and Alzheimer's disease.