Internal Medicine
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Ozanimod Capsules (Zeposia)
Ozanimod should be prescribed to treat relapsing multiple sclerosis, including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.
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Cannabis for Mental Health Disorders: Follow the Evidence
In a review of 83 eligible studies, researchers found little evidence to support the efficacy of cannabinoids to treat depressive disorders, anxiety disorders, or several other mental health disorders.
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The Cascade Effect: Calcium Channel Blockers and High Blood Pressure
Many older adults who are prescribed calcium channel blockers subsequently receive a loop diuretic. Awareness of this common cascade may reduce unnecessary prescribing and potential harm.
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More Mediterranean Diet Benefits: Diverse Microbiomes, Better Health Among Seniors
A randomized, multicenter study showed that eating a Mediterranean diet for one year improved the diversity of the gut microbiome in older subjects and was associated with reduced frailty and better health.
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Type of Provider and Opioid Use in New-Onset Low Back Pain
When compared to an initial visit with a primary care physician, patients who initially received care for new-onset low back pain from a chiropractor, physical therapist, or acupuncturist had decreased odds of both early and long-term opioid use.
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Brief, Targeted Intervention to Stop Smoking
A one-minute intervention giving facts about the health impact of smoking was presented to 787 men waiting to be seen in Hong Kong emergency rooms. At a six-month follow-up, investigators found a significantly higher abstinence rate in the intervention group.
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Social Media Use and Disordered Eating in Young Adolescents
The authors of this exploratory study in 996 young adolescents found an association between time spent on social media, number of social media accounts, and evidence of disordered eating behaviors.
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Black Elderberry Supplementation for Upper Respiratory Infection Symptoms
SYNOPSIS: A meta-analysis of results from four randomized, controlled clinical studies evaluating the effect of black elderberry supplementation suggests that the botanical significantly reduces upper respiratory symptoms due to common cold and influenza viruses.
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Cognitive Symptoms in Genetic Forms of Parkinson’s Disease May Help in Distinguishing the Various Types
This paper illustrates that, of the confirmed genetic forms of Parkinson’s disease, there are common cognitive and psychiatric features, thus adding to our knowledge of the clinical phenotype of these genetic forms.
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Zilucoplan for Myasthenia Gravis
Zilucoplan, a macrocyclic peptide that binds complement component C5, showed promise as an effective agent for treatment of generalized myasthenia gravis in a Phase II trial.