Internal Medicine
RSSArticles
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Vitamin D and Colon Cancer
A self-report of any vitamin D supplementation was associated with a decrease in colorectal polyps.
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Aromatherapy Reduces Pain and Other Symptoms
In people with myofascial pain syndrome receiving a trigger point injection, aromatherapy with lavender oil helped to decrease pain and anxiety and improve comfort.
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Nuts and Heart Health
This long-term, prospective study looks at changes in quantity of nut consumption and relative risk of cardiovascular disease and finds significantly lower risk when nut consumption increases by > 0.5 servings daily.
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Mahjong and Mild Cognitive Impairment
This randomized, controlled trial notes improvement in measures of executive functioning, such as organization and planning, in elderly Chinese participants with mild cognitive impairment who were selected to play mahjong three times weekly for 12 weeks.
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Gut Microbiome in Patients at Risk for Parkinson’s Disease
Certain risk factors and prodromal markers of Parkinson’s disease (PD), such as constipation and rapid eye movement sleep behavior disorder, are associated with specific bacterial compositions of the gut. However, the value of gut microbiome data to predict the risk of PD development needs further investigation.
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Auditory Startle Response as a Predictor of Recovery from Coma
Preserved habituation of the auditory startle response, performed at the bedside, indicates intact cortical structures and cortico-cortical white matter tract connections. Preservation of this reaction in patients with unresponsive wakefulness can help distinguish the vegetative state from minimally conscious state and may even predict eventual awakening.
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Oral Calcitonin Gene-Related Peptide Antagonist for Prevention of Migraine
Atogepant, an oral calcitonin gene-related peptide (CGRP) antagonist, was shown to be effective and safe for migraine prevention. This adds an additional CGRP antagonist to the growing arsenal of such medications, both oral and parenteral, for both prevention and treatment of migraine.
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A Novel Therapy for Amyotrophic Lateral Sclerosis Shows Promise
A novel drug combination was taken from an animal model and tested in a Phase II trial of patients with amyotrophic lateral sclerosis. Although there was a trend toward benefit, there were no statistically significant endpoints at the end of the trial. Future trials need to enroll a larger number of patients.
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Transthyretin Amyloidosis and Neuropathy
Wild-type transthyretin amyloidosis, referred to as “senile” amyloidosis previously, usually occurs in the aging population and affects the peripheral nerves and the heart. Usually, neurological symptoms precede cardiac symptoms.
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Diagnosis and Treatment of Attention Deficit Hyperactivity Disorder
Presenting with persistent inattentiveness and/or hyperactivity and impulsivity severe enough to interfere with functioning, and occurring in more than one setting, attention deficit hyperactivity disorder is one of the most common neurodevelopmental disorders of childhood, with evidence of impairment often continuing into adult years.