Internal Medicine
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Pralsetinib Capsules (Gavreto)
Pralsetinib should be prescribed to treat adults with metastatic RET, fusion-positive non-small cell lung cancer.
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Nuts and Heart Health
Investigators studied changes in quantity of nut consumption and relative risk of cardiovascular disease, finding significantly lower risk when nut consumption increases by > 0.5 servings daily.
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Repeat SARS-CoV-2 Infection
Whole genome sequencing confirmed that repeat infection with SARS-CoV-2 is possible, something that is consequential for vaccine use and public health.
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Dexamethasone for COVID-19 Inpatients Requiring Oxygen
Dexamethasone administration is associated with reduced 28-day mortality in oxygen-requiring COVID-19 patients, including those receiving mechanical ventilation.
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Vitamin D Deficiency and COVID-19 Infection
Investigators found the relative risk of testing positive for COVID-19 was higher for patients who likely are vitamin D deficient.
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Intermittent Fasting, Pesco-Mediterranean Diet Can Improve Health
Meta-analysis reveals pattern of better cardiovascular health among those who consume more seafood, vegetables, and fruit vs. those who live on red meat-heavy diets.
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What Is the Cause of This Regular WCT?
The ECG in the figure was obtained from an older woman who presented with hypotension. What is the rhythm?
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Clascoterone Cream 1% (Winlevi)
Clascoterone should be prescribed to treat acne vulgaris in patients age 12 years and older.
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Respiratory Syncytial Virus: Effective Prevention Still Needed
Prevention of respiratory syncytial virus infection is needed but challenging. New studies show some favorable effectiveness on infant outcomes with both vaccination of healthy pregnant women and passive single-dose immunization of prematurely born babies.
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Is Isolated Diastolic Hypertension a Disease?
An analysis of three large prospective databases showed the 2017 American College of Cardiology/American Heart Association revised definition of isolated diastolic hypertension as > 80 mmHg rather than the previous definition of > 90 mmHg resulted in a 5% higher prevalence of diastolic hypertension.